53 years old - PSA of 4.67

[u/Eggsalad13]

Due to my family history (father diagnosed at 52 and Grandfather died of prostrate cancer) went to urologist after finding out my PSA was 4.67. Urologist wants me to get a biopsy (scheduled in Sept).

What questions should I be asking? Anything I should be doing now?

[u/amp1212]

A biopsy at this point is reasonable. Have you had an MRI? These days, docs often do an MRI first, so that they can target particular things in the prostate. That's not standard everywhere, but if you're in the States, it might not hurt to ask because its now usually done that way.

It gives a bit more assurance that the biopsy represents stuff that might be causing a problem.

[u/Eggsalad13 → u/amp1212]

Thanks

[u/callmegorn]

Absolutely do the MRI first. This will provide you with two bits of critical information: the size of the prostate (to put the PSA into proper perspective), and any areas of concern for the biopsy to target.

[u/Eggsalad13 → u/callmegorn]

Thanks

[u/planck1313]

Best modern practice is to get an MRI before the biopsy so that any suspicious zones found by the MRI can be specifically targeted in the biopsy, otherwise they are just sampling at random.

[u/Eggsalad13 → u/planck1313]

Thanks

[u/jkurology]

Prior to the biopsy get Germline testing-you are at high risk for a germline variant and knowing that is important for you and for your children. Data supports an MRI prior to a biopsy

[u/Eggsalad13 → u/jkurology]

Thanks

[u/That_Win_6798]

My husband diagnosed at 53, his father and two uncles were also diagnosed with PC with aunts and cousins also battling cancer. Genetic testing confirmed BRCA2 gene mutation. He now has a team of doctors guiding his treatment plan. Treat early and monitor closely. You might inquire about genetic testing, if available.

[u/Eggsalad13 → u/That_Win_6798]

Thanks