r/lungcancer • u/GoldAd799 • 10d ago

Targeted therapy no longer working

A family member was diagnosed with T2bN3M0 lung cancer a year ago. They were started on targeted therapy Osimertinib (otherwise called Tagrisso I believe). Initially this showed some really positive results, with the main mass reducing in size. However on the last scan, it showed the tumours have now increased in size. Now waiting to hear whether chemo/radiation will be the next steps. Has anyone else/family members also experienced targeted therapy no longer working? What treatment came next and how did this affect prognosis?

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u/GoldAd799 9d ago

Thanks both. Have just found out that radiotherapy is not an option due to the cancers location, so they are going to try chemotherapy (4 sessions over a 12 week period). Any tips on how we as a family can support them going through this? As I know the side effects can be tough. Wishing you all the best on your journeys

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u/Mysterious-Two2103 9d ago

If your family memeber is able to get fat adapted by not eating sugars, carbs, starches they can fast for 36-72 hours before chemo to put their normal cells into a protective state so the chemo will not make them sick.

You can research it and hear peoples testimonies on youtube to see what and how they did it.